Could the Time Be Near at Hand to Turn Gray Hair Back to Black? Taisho Pharmaceutical Confirms Effectiveness in Improving Gray Hair through Clinical Trials

Taisho Pharmaceutical, which has been conducting research on the improvement of gray hair, announced that it has confirmed a new effect of improving gray hair in human clinical trials. Gray hair with a touch of austerity is of course attractive, but many men would like to keep their natural black hair as much as possible. Such a desire is not a pipe dream, and the time when gray hair can be turned back into black hair may be just around the corner.

The improvement in gray hairs is obvious in the pics!

The company had previously announced the possibility that an ingredient called Botanpi Extract could turn gray hair back into black hair, and that Black Reverse Peptide 1 could enhance the effect of turning gray hair back into black hair. In this announcement, the company reported that the synergistic effect of Botanpi Extract and Black Reverse Peptide 1 was actually confirmed to improve gray hair. The images below show before and after of the actual clinical trial. It can be clearly seen that the area where gray hair was growing has been transformed into black hair.

Hair before it leaves the pore is originally white! So what causes black hair to turn gray?

According to the company’s release, all hair is originally white before it emerges from the pores. Hair is produced by the proliferation and differentiation of hair matrix cells in the hair root. The hair matrix cells have no pigment and produce black hair by receiving pigment from melanocytes, which produce pigment called melanin. This is why hair is naturally white. In other words, if for some reason the hair matrix cells do not receive pigment and hair is produced without pigment, it becomes gray hair. There are various possible causes for this, such as the absence of melanocytes, or if melanocytes do exist, they do not produce melanin.

Action of Botanpi Extract

Botanpi-extract is extracted from the root bark of the button flower, a beautiful flower known as “the king of the hundred flowers,” and has been used as a herbal medicine since ancient times. The company discovered that botanpi extract is an ingredient that stimulates the production of mitochondria-activating enzyme mitoligase. According to a report by Professor Shigeru Yanagi of Gakushuin University, a decrease in mitrigase leads to hair loss and gray hair development. Botanpi extract acts on a wide range of cells in the hair follicle and inhibits the decline of mitrigase. In fact, when botanpi extract was applied to hair follicles, the activity of melanosomes, the organ that produces melanin, was activated.

Action of Black Reverse Peptide 1

The company focused on Black Reverse Peptide 1 as an ingredient that enhances the effects of button pea extract. This peptide, also known as Greyverse, was developed by Canadian manufacturer Lucas Meyer Cosmetics. This ingredient acts directly on melanocytes to stimulate their proliferation and melanin production. When acting on hair follicles, it was confirmed that the synergistic effect with Botanpi extract raises the amount of melanin in hair follicles.

This newly confirmed combination of Botanpi extract and Black Reverse Peptide 1 improves gray hair. Is this the arrival of an era in which gray hair dyeing will no longer be necessary? The company plans to continue its research on total care for scalp and hair, including thinning hair and hair quality, aiming for an era in which gray hair can be cured.